8b723d7347a3d1b9ef1d50eae6bf785dEyelashes have a very specific growth cycle and anatomy. In general, this period of growth is called the anagen phase and lasts between 30 to 45 daysOnly about 40% of the upper lashes and 15% of the lower lashes are in the anagen phase at any one point-in-time.

Each lash will grow to a specific length and then stop. It is important to know the formulations of lash growth serums to ensure they do more than just hydrate the skin and help to prevent fallout (we’re looking at you Castor oil! 🙊). This post serves as a review of the specific formulations and ingredients that can aid in marked growth of eyelashes.

Keep an eye out for similar substances in your own respective lash growth serums or consult your favorite SeneGence/LipSense rep should you have any additional questions.

Ingredient Analysis (in order of abundance) of SeneGence’s LashExtend:

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Ingredient #1: Water (Aqua)

Water (structural formula)

Also known as dihydrogen monixide, water… do I really need to cover this one?

Ingredient #2: Glycerin

Glycerin (structural formula).png

Glycerin (glycerol) is a natural substance in all lipids (fats/oils, particularly those of the skin) and serves as a skin-replenishing and restorative agent. This substance draws moisture (humectant) and helps the skin to maintain a soft, supple feel by drawing moisture from its surroundings and applying specifically to the area to which it is applied.




Ingredient #3: Myristoyl Pentapeptide-17


This ingredient is essential to the process and life cycle of eyelash growth. Ensure that any growth serum you purchase contains this substance; else it may just be a conditioning agent that helps to prevent fallout but does not influence the growth of eyelashes. Unlike other peptides, it plays a dual role, working for both the skin and lashes as an antioxidant and in the delivery of peptides needed for hair growth.

The basic building block of every cell in the human body is protein. Myristoyl Pentapeptide-17 delivers these proteins directly to the area of your lashes where it is most needed for growth. Myristoyl Pentapeptide-17 also protects the skin from and neutralizes damaging free radicals, which are a result of too much sun exposure or encountering environmental pollutants.

Ingredient #4: Camellia Sinensis (White Tea) Extract


This substance is the most expensive of the ingredients included in LashExtend and serves a number of roles in addition to enhancing the delivery of ingredients #11 and 12. White tea has been scientifically proven to protect the skin from oxidative stress and immune cell damage caused by sunlight and exposure while also stimulating healthy skin growth and regeneration.

Ingredient #5: Chamomilla Recutita (Matricaria) Extract



You’re probably familiar with chamomile tea and have likely seen these beautiful flowers growing out in a field. This delicate little flower serves a much greater benefit than use within a soothing tea. Initial studies show chamomile (and a-Bisabolol, the main active principle of the herb) demonstrating great benefits for skin and hair.


It serves as a potent emollient and has moisturizing properties, and should be used concurrently with glycerol/glycerin. Be sure your choice of formulation of lash growth serum has these two components. Research suggests antispasmodic, anxiolytic, anti-inflammatory and some antimutagenic (anticancer) and cholesterol-lowering effects for chamomile.

Ingredients #6-9: Hydroxyethylcellulose, Sodium Chloride, Monobasic Sodium Phosphate, Dibasic Sodium Phosphate (The Thickening Agents)

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We’ve seen these ingredients a number of times in our other cosmetics! Seems to consistently be a staple of skin protecting formulations and is used as a thickening agent. Thickening agents are imperative in formulations used on the eyelashes as much of what benefits the hair does not benefit the cells in the eyes. Thickening agents help to keep these substances from running down the skin and into the eye.

Ingredient #10: Disodium EDTA (ethylenediaminetetraacetic acid)

Disodium edta (structural formula).png

Primarily serving as a preservative, chelator and stabilizer, Disodium EDTA is a metal chelator that counteracts the adverse effects of hard water and other contaminants by binding with heavy metal ions. This prevents the metals from being deposited onto the skin, hair and scalp. You’ll notice Ingredient #15 is an iron oxide. This combination prevents LashExtend from deteriorating, allows it to maintain its clarity and prevents it from spoiling.

Ingredient #11-15: Phenoxyethanol, Tropolone, Quaternium-15, and Iron Oxides – The “May Contain” Ingredients

Phenoxyethanol (structural formula).png

Used sparingly in this formulation, phenoxyethanol is a preservative but can be a potential allergen if injected to the skin. Now of course, LashExtend isn’t intended from intravenous use, yet it is a rare feat to assemble any substance in which any and all persons exposed to it will not result in a handful of allergic reactions. You will, however, likely know if you are allergic to this substance. You see, it is used most commonly as a preservative in vaccines. If you have a severe allergic reaction to a vaccine, please ask your health provider if this ingredient could result in a reaction. 

The remainder of these ingredients serve as antimicrobial agents to ensure your product can last months on end! My suggested “use by” time is 6 months but I could find no documented expiration of LashExtend.

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What’s the deal with “May Contain” ingredients?

In case you were ever wondering why SeneGence has a number of products with a “May Contain” set of ingredients, know that this is both a CYA and meant to protect the customer. You see, there are people in the world who have extremely rare and sensitive allergies to a number of different substances.

This list covers any and all substances that may be in one color/shade/line and not the other, any substances that can be the metabolic products of the original ingredients, and any substances that may be transferred from other machinery. Iron Oxides in particular are in case there is a portion of the machine that may be rusting. To ensure there’s little chance of a customer using a product containing the smallest, trace amounts of substance, however unlikely, SeneGence lists every. single. one.

At first, seeing the “May Contain” ingredients list made me feel concerned. Having read and researched this, I now worry when other companies DON’T list their “May Contains”.



  1. How does it exactly aid the lashes growth? By providing hydration, the appropriate proteins, and cell stimulating extracts and reagents designed to target the lashes at the stage of their growth.
  2. What causes other similar products to change eye color but not ours? Some lash serums contain various pigments that aid in darkening lash hair to aid in the appearance of thicker lashes. These pigments are what discolor eyes. Our clear formulation of LashExtend does not include pigments. The color LashExtend that serves as dual eyeliner contains pigments that are gentle to the skin and remains on the surface of skin (does not penetrate the epidermis, much like any other liquid eyeliner) while still delivering the nutrients needed for growth.
  3. How long does it need to be on for it to be mostly absorbed before wiping off (prior to shadow application)? While skin absorption varies from person to person, if the substance has lost its sheen (shiny appearance), it will then allow for ease of application of eyeshadow.
  4. Any others? If after reading our post you still have questions, come to our Facebook group and ask! 

Results and the Bottom (Lash) Line!

In conclusion, you will see a visible effect in 2-4 weeks. Best results are noted after 6 weeks. Hair on the eyelashes and eyebrows have a very short active growth phase of only about 30-45 days. Approximately 40% of the eyelashes are in this phase. The entire duration of lifecycle for the eyelashes is 3-4 months. If you’re interested, but do not have a friend who is a SeneGence Representative and can provide this product, feel free to comment below.


  1. Long, Walter S. (14 January 1916 – 13 January 1917). “The composition of commercial fruit extracts”. Transactions of the Kansas Academy of Science. 28: 157–161. doi:10.2307/3624347. JSTOR 3624347.
  2. Lawrie, James W. (1928) Glycerol and the glycols – production, properties and analysis. The Chemical Catalog Company, Inc., New York, NY.
  3. Rusak, Komes, Likic, et al. Phenolic content and antioxidative capacity of green and white tea extracts depending on extraction conditions and the solvent used. Food Chemistry. Volume 110, Issue 4, 15 October 2008, Pages 852–858.
  4. Kamatou, G. P., & Viljoen, A. M. (2010). A review of the application and pharmacological properties of α-bisabolol and α-bisabolol-rich oils. Journal of the American Oil Chemists’ Society, 87(1), 1-7.
  5. Dawid-Pać, R. (2013). Medicinal plants used in treatment of inflammatory skin diseases. Advances in Dermatology and Allergology/Postȩpy Dermatologii I Alergologii, 30(3), 170.
  6. Morgan, M. (1996). Chamomile from a clinical perspective. Modern Phytotherapist, 3(2), 17-19.
  7. Andersen, F. A. (1999). Final report on the safety assessment of Bisabolol. International journal of toxicology, 18(3 suppl), 33-40.
  8. Srivastava J, Shankar E, Gupta S (2011) Chamomile: A herbal medicine of the past with bright future. Mol Med 3: 895–901.
  9. Safety Assessment of Chamomilla Recutita-Derived Ingredients as Used in Cosmetics Final Report. Cosmetic Ingredient Review; January 9, 2014.
  10. Wineski LE, English AW (1989). “Phenoxyethanol as a nontoxic preservative in the dissection laboratory”. Acta Anat (Basel). 136 (2): 155–8. doi:10.1159/000146816. PMID 2816264.
  11. Lowe I, Southern J (1994). “The antimicrobial activity of phenoxyethanol in vaccines”. Lett Appl Microbiol. 18 (2): 115–6. doi:10.1111/j.1472-765X.1994.tb00820.x. PMID 7764595.
  12. Pietra, F., “Seven-membered conjugated carbo- and heterocyclic compounds and their homoconjugated analogs and metal complexes. Synthesis, biosynthesis, structure, and reactivity”, Chemical Reviews 1973, volume 73, 293-364. doi:10.1021/cr60284a002